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Engineered Ribosyl-1-Kinase Enables Concise Synthesis of Molnupiravir, an Antiviral for COVID-19.
McIntosh, John A; Benkovics, Tamas; Silverman, Steven M; Huffman, Mark A; Kong, Jongrock; Maligres, Peter E; Itoh, Tetsuji; Yang, Hao; Verma, Deeptak; Pan, Weilan; Ho, Hsing-I; Vroom, Jonathan; Knight, Anders M; Hurtak, Jessica A; Klapars, Artis; Fryszkowska, Anna; Morris, William J; Strotman, Neil A; Murphy, Grant S; Maloney, Kevin M; Fier, Patrick S.
Afiliação
  • McIntosh JA; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Benkovics T; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Silverman SM; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Huffman MA; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Kong J; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Maligres PE; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Itoh T; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Yang H; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Verma D; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Pan W; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Ho HI; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Vroom J; Codexis, Inc., 200 Penobscot Drive, Redwood City, California 94063, United States.
  • Knight AM; Codexis, Inc., 200 Penobscot Drive, Redwood City, California 94063, United States.
  • Hurtak JA; Codexis, Inc., 200 Penobscot Drive, Redwood City, California 94063, United States.
  • Klapars A; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Fryszkowska A; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Morris WJ; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Strotman NA; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Murphy GS; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Maloney KM; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
  • Fier PS; Department of Process Research and Development, Merck & Co., Inc., Rahway, New Jersey 07065, United States.
ACS Cent Sci ; 7(12): 1980-1985, 2021 Dec 22.
Article em En | MEDLINE | ID: mdl-34963891

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Cent Sci Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: ACS Cent Sci Ano de publicação: 2021 Tipo de documento: Article