Acute worsening of native lung fibrosis after single lung transplantation for pulmonary fibrosis: two case reports.
J Med Case Rep
; 16(1): 2, 2022 Jan 03.
Article
em En
| MEDLINE
| ID: mdl-34980231
ABSTRACT
BACKGROUND:
In patients receiving single lung transplantation for idiopathic pulmonary fibrosis, worsening of fibrosis of the native lung is usually progressive over time, with no significant effects on gas exchange. CASE PRESENTATION Here, we describe the cases of two Caucasian male recipients of single lung transplants for idiopathic pulmonary fibrosis, 65 and 62 years of age, who exhibited acute worsening of lung fibrosis after an episode of serious viral infection (cytomegalovirus primo-infection in one case and COVID-19 in the other). In both cases, along with opacification of the native lung over several days, the patients presented acute respiratory failure that required the use of high-flow nasal oxygen therapy. Eventually, hypoxemic respiratory failure resolved, but with rapid progression of fibrosis of the native lung.CONCLUSION:
We conclude that acute worsening of fibrosis on the native lung secondary to a severe viral infection should be added to the list of potential complications developing on the native lung after single lung transplantation for idiopathic pulmonary fibrosis.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Transplante de Pulmão
/
Fibrose Pulmonar Idiopática
/
COVID-19
Limite:
Humans
/
Male
Idioma:
En
Revista:
J Med Case Rep
Ano de publicação:
2022
Tipo de documento:
Article