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Review of Neurologic Comorbidities in Hospitalized Patients With Opioid Abuse.
Nelson, Kevin R; Dolbec, Katelyn; Watson, William; Yuan, Hanwen; Ibraheem, Mam.
Afiliação
  • Nelson KR; Department of Neurology (KRN, KD, WW, MI), University of Kentucky, Lexington; Department of Neurology (WW), Uniformed Services University, Bethesda, MD; Performance Analytics Center of Excellence (HY), University of Kentucky Health Care, Lexington; Department of Epidemiology (MI), University of Kent
  • Dolbec K; Department of Neurology (KRN, KD, WW, MI), University of Kentucky, Lexington; Department of Neurology (WW), Uniformed Services University, Bethesda, MD; Performance Analytics Center of Excellence (HY), University of Kentucky Health Care, Lexington; Department of Epidemiology (MI), University of Kent
  • Watson W; Department of Neurology (KRN, KD, WW, MI), University of Kentucky, Lexington; Department of Neurology (WW), Uniformed Services University, Bethesda, MD; Performance Analytics Center of Excellence (HY), University of Kentucky Health Care, Lexington; Department of Epidemiology (MI), University of Kent
  • Yuan H; Department of Neurology (KRN, KD, WW, MI), University of Kentucky, Lexington; Department of Neurology (WW), Uniformed Services University, Bethesda, MD; Performance Analytics Center of Excellence (HY), University of Kentucky Health Care, Lexington; Department of Epidemiology (MI), University of Kent
  • Ibraheem M; Department of Neurology (KRN, KD, WW, MI), University of Kentucky, Lexington; Department of Neurology (WW), Uniformed Services University, Bethesda, MD; Performance Analytics Center of Excellence (HY), University of Kentucky Health Care, Lexington; Department of Epidemiology (MI), University of Kent
Neurol Clin Pract ; 11(6): 527-533, 2021 Dec.
Article em En | MEDLINE | ID: mdl-34992960
ABSTRACT
PURPOSE OF REVIEW To determine the prevalence and burden of neurologic comorbidities in hospitalized patients with opioid abuse. RECENT

FINDINGS:

From 1 year of hospital discharges, 2,182 patients with opioid abuse were identified (prevalence 6.3%), with abuse greater among younger patients (p < 0.0001), women (p < 0.0001), Whites (p < 0.0001), and urban population (p = 0.028). Matching for age, sex, race, and urban-rural residence, 347 patients were reviewed, and 179 (52%) had a neurologic comorbidity. The comorbidities frequently overlapped and included encephalopathy (130), neuromuscular disorders (42), seizures (23), spine disorders (23), strokes (20), CNS infections (3), and movement disorders (2). Abuse patients with neurologic comorbidities experienced substantially greater number of hospital and intensive care unit days and mortality, independent of overdose.

SUMMARY:

Neurologic comorbidities are a frequent and heretofore underappreciated contributor to the disease burden of hospitalized patients with opioid abuse. The importance of neurologic comorbidities should be included in the public health discussions surrounding the opioid epidemic.

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Neurol Clin Pract Ano de publicação: 2021 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies / Risk_factors_studies Idioma: En Revista: Neurol Clin Pract Ano de publicação: 2021 Tipo de documento: Article