Your browser doesn't support javascript.
loading
Protective effects of physical activity in colon cancer and underlying mechanisms: A review of epidemiological and biological evidence.
Wang, Tianzhen; Zhang, Ying; Taaffe, Dennis R; Kim, Jin-Soo; Luo, Hao; Yang, Lirui; Fairman, Ciaran M; Qiao, Yuandong; Newton, Robert U; Galvão, Daniel A.
Afiliação
  • Wang T; Department of Pathology, Harbin Medical University, Harbin, 150081, China; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Zhang Y; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia; Department of Physiology, Harbin Medical University, Harbin, 150081, China.
  • Taaffe DR; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Kim JS; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Luo H; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Yang L; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Fairman CM; Exercise Science Department, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.
  • Qiao Y; Laboratory of Medical Genetics, Harbin Medical University, Harbin, 150081, China.
  • Newton RU; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia.
  • Galvão DA; Exercise Medicine Research Institute, Edith Cowan University, Joondalup, WA, Australia; School of Medical and Health Sciences, Edith Cowan University, Joondalup, WA, Australia. Electronic address: d.galvao@ecu.edu.au.
Crit Rev Oncol Hematol ; 170: 103578, 2022 Feb.
Article em En | MEDLINE | ID: mdl-35007701
ABSTRACT
Numerous epidemiological studies indicate that physical activity has a protective effect against colon cancer development and progression. Further, the relevant biological mechanisms where physical activity or exercise may improve survival have also been initially examined. In this review, we provide an overview of the epidemiological evidence to date which comprises 16 cohort studies of the effects of physical activity on colon cancer outcomes including cancer recurrence, cancer-specific and overall survival. Moreover, we present four potential mechanisms involving shear pressure, systemic milieu alteration, extracellular vesicles, and immune function by which physical activity and exercise may favorably impact colon cancer. Research currently in progress will provide definitive evidence of survival benefits resulting from exercise and future work will help clarify the role of targeted exercise and the relevant mechanisms involved.
Assuntos
Palavras-chave
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 Base de dados: MEDLINE Assunto principal: Neoplasias do Colo / Recidiva Local de Neoplasia Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Crit Rev Oncol Hematol Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 Base de dados: MEDLINE Assunto principal: Neoplasias do Colo / Recidiva Local de Neoplasia Tipo de estudo: Observational_studies / Risk_factors_studies Limite: Humans Idioma: En Revista: Crit Rev Oncol Hematol Ano de publicação: 2022 Tipo de documento: Article