Comparative Chiral Separation of Thalidomide Class of Drugs Using Polysaccharide-Type Stationary Phases with Emphasis on Elution Order and Hysteresis in Polar Organic Mode.

Foroughbakhshfasaei, Mohammadhassan; Dobó, Máté; Boda, Francisc; Szabó, Zoltán-István; Tóth, Gergo

Foroughbakhshfasaei, Mohammadhassan; Dobó, Máté; Boda, Francisc; Szabó, Zoltán-István; Tóth, Gergo.

Afiliação

Foroughbakhshfasaei M; Department of Pharmaceutical Chemistry, Semmelweis University, Hogyes E. Str. 9, H-1085 Budapest, Hungary.
Dobó M; Department of Pharmaceutical Chemistry, Semmelweis University, Hogyes E. Str. 9, H-1085 Budapest, Hungary.
Boda F; Department of General and Inorganic Chemistry, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Gh. Marinescu 38, RO-540139 Targu Mures, Romania.
Szabó ZI; Department of Pharmaceutical Industry and Management, George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Gh. Marinescu 38, RO-540139 Targu Mures, Romania.
Tóth G; Department of Pharmaceutical Chemistry, Semmelweis University, Hogyes E. Str. 9, H-1085 Budapest, Hungary.

Molecules ; 27(1)2021 Dec 24.

Article em En | MEDLINE | ID: mdl-35011343

Assuntos

Fracionamento Químico/métodos; Fenômenos de Química Orgânica; Polissacarídeos/química; Talidomida/química; Talidomida/isolamento & purificação; Estrutura Molecular; Análise Espectral; Talidomida/análogos & derivados

Palavras-chave

chiral HPLC; enantiomer elution order; enantioseparation; hysteresis; polar organic mode; polysaccharide-type stationary phase; thalidomide

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Polissacarídeos / Talidomida / Fenômenos de Química Orgânica / Fracionamento Químico Idioma: En Revista: Molecules Ano de publicação: 2021 Tipo de documento: Article

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