L-5-hydroxytryptophan attenuates positive psychotic symptoms induced by D-amphetamine.
Psychiatry Res
; 22(4): 283-9, 1987 Dec.
Article
em En
| MEDLINE
| ID: mdl-3501597
ABSTRACT
Brain serotonin has been hypothesized to be involved in the modulation of psychotic symptoms in at least some forms of schizophrenia. We examined the effects of the serotonin precursor L-5-hydroxytryptophan (5HTP) on D-amphetamine induction of acute psychotic symptoms in schizophrenic patients. Preadministration with 5HTP significantly antagonized amphetamine-elicited elevations in thought disturbance, activation, and hallucinations.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psicologia do Esquizofrênico
/
5-Hidroxitriptofano
/
Dextroanfetamina
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Psychiatry Res
Ano de publicação:
1987
Tipo de documento:
Article