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Analysis of antibody binding specificities in twin and SNP-genotyped cohorts reveals that antiviral antibody epitope selection is a heritable trait.
Venkataraman, Thiagarajan; Valencia, Cristian; Mangino, Massimo; Morgenlander, William; Clipman, Steven J; Liechti, Thomas; Valencia, Ana; Christofidou, Paraskevi; Spector, Tim; Roederer, Mario; Duggal, Priya; Larman, H Benjamin.
Afiliação
  • Venkataraman T; Institute for Cell Engineering, Division of Immunology, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.
  • Valencia C; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Mangino M; Department of Twin Research & Genetic Epidemiology, King's College of London, London, UK; NIHR Biomedical Research Centre at Guy's and St Thomas' Foundation Trust, London SE1 9RT, UK.
  • Morgenlander W; Institute for Cell Engineering, Division of Immunology, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA.
  • Clipman SJ; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Liechti T; ImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
  • Valencia A; School of Medicine, Universidad Pontificia Bolivariana, Medellín, Colombia.
  • Christofidou P; Department of Twin Research & Genetic Epidemiology, King's College of London, London, UK.
  • Spector T; Department of Twin Research & Genetic Epidemiology, King's College of London, London, UK.
  • Roederer M; ImmunoTechnology Section, Vaccine Research Center, NIAID, NIH, Bethesda, MD, USA.
  • Duggal P; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA; Department of International Health, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
  • Larman HB; Institute for Cell Engineering, Division of Immunology, Department of Pathology, Johns Hopkins University, Baltimore, MD, USA. Electronic address: hlarman1@jhu.edu.
Immunity ; 55(1): 174-184.e5, 2022 01 11.
Article em En | MEDLINE | ID: mdl-35021055
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Epitopos Imunodominantes / Herpesvirus Humano 4 / Antígenos Nucleares do Vírus Epstein-Barr / Infecções por Vírus Epstein-Barr / Genótipo / Anticorpos Antivirais / Epitopos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Immunity Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Virais / Epitopos Imunodominantes / Herpesvirus Humano 4 / Antígenos Nucleares do Vírus Epstein-Barr / Infecções por Vírus Epstein-Barr / Genótipo / Anticorpos Antivirais / Epitopos Tipo de estudo: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adolescent / Adult / Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Immunity Ano de publicação: 2022 Tipo de documento: Article