A case of pediatric psoriasis achieving remission after allogenic bone marrow transplantation.
Turk J Pediatr
; 63(6): 1078-1083, 2021.
Article
em En
| MEDLINE
| ID: mdl-35023659
ABSTRACT
BACKGROUND:
Psoriasis is an inflammatory skin disease in which the cells and molecules of innate and adaptive immunity are involved in the pathogenesis. Aplastic anemia is a bone marrow deficiency syndrome that is characterized by an extreme reduction in the number of blood cells as a result of failure in hematopoiesis. Allogenic hematopoietic stem cell transplantation is a promising treatment for Aplastic Anemia and it is important to note that other comorbid diseases like psoriasis- since both have some common pathogenetic mechanisims- might achieve remission after treatment. CASE We present a 12-years-old male patient who underwent bone marrow transplantation for aplastic anemia and his psoriasis vulgaris lesions completely regressed. The final follow-up visit on day 150 also revealed no sign of the pre-transplantation skin and scalp lesions.CONCLUSIONS:
This is the first case of pediatric psoriasis together with aplastic anemia that achieved complete remission of psoriasis after bone marrow transplantation. Our case report needs to be supported by prospective studies involving larger patient populations.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Psoríase
/
Transplante de Células-Tronco Hematopoéticas
/
Anemia Aplástica
Tipo de estudo:
Observational_studies
Limite:
Child
/
Humans
/
Male
Idioma:
En
Revista:
Turk J Pediatr
Ano de publicação:
2021
Tipo de documento:
Article