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Inhibition of the deubiquitinating enzyme USP47 as a novel targeted therapy for hematologic malignancies expressing mutant EZH2.
Yang, Jing; Weisberg, Ellen L; Qi, Shuang; Ni, Wei; Mei, Husheng; Wang, Zuowei; Meng, Chengcheng; Zhang, Shengzhe; Hou, Mingqi; Qi, Ziping; Wang, Aoli; Jiang, Yunyun; Jiang, Zongru; Huang, Tao; Liu, Qingwang; Magin, Robert S; Doherty, Laura; Wang, Wenchao; Liu, Jing; Buhrlage, Sara J; Liu, Qingsong; Griffin, James D.
Afiliação
  • Yang J; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, PR China.
  • Weisberg EL; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, PR China.
  • Qi S; Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA.
  • Ni W; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.
  • Mei H; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wang Z; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Meng C; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, PR China.
  • Zhang S; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, PR China.
  • Hou M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Qi Z; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Wang A; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, PR China.
  • Jiang Y; University of Science and Technology of China, Hefei, Anhui, 230036, PR China.
  • Jiang Z; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, PR China.
  • Huang T; University of Science and Technology of China, Hefei, Anhui, 230036, PR China.
  • Liu Q; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Magin RS; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Doherty L; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Wang W; Department of Medicine, Harvard Medical School, Boston, MA, USA.
  • Liu J; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, PR China.
  • Buhrlage SJ; University of Science and Technology of China, Hefei, Anhui, 230036, PR China.
  • Liu Q; Anhui Province Key Laboratory of Medical Physics and Technology, Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei, 230031, PR China.
  • Griffin JD; Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, 230031, PR China.
Leukemia ; 36(4): 1048-1057, 2022 04.
Article em En | MEDLINE | ID: mdl-35034955

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histonas / Neoplasias Hematológicas Limite: Animals / Humans Idioma: En Revista: Leukemia Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Histonas / Neoplasias Hematológicas Limite: Animals / Humans Idioma: En Revista: Leukemia Ano de publicação: 2022 Tipo de documento: Article