Drosophila ZIP13 over-expression or transferrin1 RNAi influences the muscle degeneration of Pink1 RNAi by elevating iron levels in mitochondria.

Xue, Jinsong; Li, Guangying; Ji, Xiaowen; Liu, Zhi-Hua; Wang, Hui-Li; Xiao, Guiran

Xue, Jinsong; Li, Guangying; Ji, Xiaowen; Liu, Zhi-Hua; Wang, Hui-Li; Xiao, Guiran.

Afiliação

Xue J; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, China.
Li G; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, China.
Ji X; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, China.
Liu ZH; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, China.
Wang HL; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, China.
Xiao G; Key Laboratory of Metabolism and Regulation for Major Diseases of Anhui Higher Education Institutes, School of Food and Biological Engineering, Hefei University of Technology, Hefei, Anhui, China.

J Neurochem ; 160(5): 540-555, 2022 03.

Article em En | MEDLINE | ID: mdl-35038358

Assuntos

Proteínas de Drosophila; Doença de Parkinson; Animais; Drosophila/metabolismo; Proteínas de Drosophila/genética; Proteínas de Drosophila/metabolismo; Humanos; Ferro/metabolismo; Mitocôndrias/metabolismo; Músculos; Doença de Parkinson/genética; Doença de Parkinson/metabolismo; Proteínas Serina-Treonina Quinases; Interferência de RNA; Ubiquitina-Proteína Ligases/genética; Ubiquitina-Proteína Ligases/metabolismo

Palavras-chave

Drosophila; Pink1; activity; iron; mitochondria complex

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doença de Parkinson / Proteínas de Drosophila Limite: Animals / Humans Idioma: En Revista: J Neurochem Ano de publicação: 2022 Tipo de documento: Article

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