Recent Advances in Structure, Function, and Pharmacology of Class A Lipid GPCRs: Opportunities and Challenges for Drug Discovery.

Krishna Deepak, R N V; Verma, Ravi Kumar; Hartono, Yossa Dwi; Yew, Wen Shan; Fan, Hao

Krishna Deepak, R N V; Verma, Ravi Kumar; Hartono, Yossa Dwi; Yew, Wen Shan; Fan, Hao.

Afiliação

Krishna Deepak RNV; Bioinformatics Institute, A*STAR, 30 Biopolis Street, Matrix #07-01, Singapore 138671, Singapore.
Verma RK; Bioinformatics Institute, A*STAR, 30 Biopolis Street, Matrix #07-01, Singapore 138671, Singapore.
Hartono YD; Bioinformatics Institute, A*STAR, 30 Biopolis Street, Matrix #07-01, Singapore 138671, Singapore.
Yew WS; Synthetic Biology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore.
Fan H; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, Singapore 117597, Singapore.

Pharmaceuticals (Basel) ; 15(1)2021 Dec 22.

Article em En | MEDLINE | ID: mdl-35056070

Palavras-chave

antibody; cannabinoid receptor; computational methods; drug discovery; free fatty acid receptor; leukotriene receptor; ligand access; lipid GPCR; lysophosphatidic acid receptor; orthosteric and allosteric binding sites; platelet-activating factor receptor; prostaglandin receptor; sphingosine-1-phosphate receptor

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Idioma: En Revista: Pharmaceuticals (Basel) Ano de publicação: 2021 Tipo de documento: Article

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