Transcutaneous Electrical Acustimulation Improved the Quality of Life in Patients With Diarrhea-Irritable Bowel Syndrome.
Neuromodulation
; 25(8): 1165-1172, 2022 Dec.
Article
em En
| MEDLINE
| ID: mdl-35088760
ABSTRACT
BACKGROUND AND AIM:
Patients with diarrhea-dominant irritable bowel syndrome (IBS-D) experience abdominal pain and reduced quality of life and need effective treatments. This study aimed to evaluate whether transcutaneous electrical acustimulation (TEA) at two acupuncture points, LI4 and ST36, could improve pain and quality of life of patients with IBS-D. MATERIALS ANDMETHODS:
A total of 42 patients with IBS-D who met the Rome IV criteria were randomly divided into two groups TEA and sham-TEA. TEA was performed through acupoints Hegu (LI4) and Zusanli (ST36) for one hour twice daily for one month, using previously established parameters; sham-TEA was delivered in the same way as TEA but without actual electrical current stimulation.RESULTS:
The sham-TEA group showed a significantly higher rate of drop-out than the TEA group (29% vs 0%, p = 0.021). TEA, but not sham-TEA, significantly improved quality of life (before 78.55 ± 9.62, after 85.97 ± 9.49, p < 0.0001). Both TEA and sham-TEA reduced abdominal pain; however, TEA was more potent than sham-TEA (p = 0.014). The IBS symptom severity scale score was reduced by both TEA and sham-TEA. Autonomic functions assessed by plasma norepinephrine and pancreatic polypeptide were not altered with TEA, nor was interleukin 10 or interleukin 6.CONCLUSIONS:
TEA at LI4 and ST36 improves abdominal pain and quality of life of patients with IBS-D, probably mediated by mechanisms other than autonomic function or inflammatory cytokines.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
2_ODS3
/
3_ND
Base de dados:
MEDLINE
Assunto principal:
Terapia por Acupuntura
/
Síndrome do Intestino Irritável
Tipo de estudo:
Clinical_trials
/
Etiology_studies
Aspecto:
Patient_preference
Limite:
Humans
Idioma:
En
Revista:
Neuromodulation
Ano de publicação:
2022
Tipo de documento:
Article