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Responder analysis to demonstrate the effect of targeting type 2 inflammatory mechanisms with dupilumab across objective and patient-reported endpoints for patients with severe chronic rhinosinusitis with nasal polyps in the SINUS-24 and SINUS-52 studies.
Bachert, Claus; Peters, Anju T; Heffler, Enrico; Han, Joseph K; Olze, Heidi; Pfaar, Oliver; Chuang, Chien-Chia; Rout, Raj; Attre, Richa; Goga, Ledia; Jacob-Nara, Juby A; Rowe, Paul J; Deniz, Yamo; Chen, Zhen; Kamat, Siddhesh; Siddiqui, Shahid.
Afiliação
  • Bachert C; Ghent University, Ghent, Belgium.
  • Peters AT; Karolinska Institutet, Stockholm, Sweden.
  • Heffler E; The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
  • Han JK; Allergy-Immunology Division and the Sinus and Allergy Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
  • Olze H; Personalized Medicine, Asthma & Allergy - Humanitas Clinical and Research Center IRCCS, Rozzano, Milan, Italy.
  • Pfaar O; Department of Biomedical Science, Humanitas University, Milan, Italy.
  • Chuang CC; Eastern Virginia Medical School, Norfolk, Virginia, USA.
  • Rout R; Department of Otorhinolaryngology, Charité-Universitätsmedizin Berlin, Berlin, Germany.
  • Attre R; Section of Rhinology and Allergy, Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Marburg, Philipps-Universität Marburg, Marburg, Germany.
  • Goga L; Sanofi, Cambridge, Massachusetts, USA.
  • Jacob-Nara JA; Sanofi, Reading, UK.
  • Rowe PJ; Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA.
  • Deniz Y; Sanofi, Cambridge, Massachusetts, USA.
  • Chen Z; Sanofi, Bridgewater, New Jersey, USA.
  • Kamat S; Sanofi, Bridgewater, New Jersey, USA.
  • Siddiqui S; Regeneron Pharmaceuticals, Inc., Tarrytown, New York, USA.
Clin Exp Allergy ; 52(2): 244-249, 2022 02.
Article em En | MEDLINE | ID: mdl-35092110

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinusite / Rinite / Pólipos Nasais Aspecto: Patient_preference Limite: Humans Idioma: En Revista: Clin Exp Allergy Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sinusite / Rinite / Pólipos Nasais Aspecto: Patient_preference Limite: Humans Idioma: En Revista: Clin Exp Allergy Ano de publicação: 2022 Tipo de documento: Article