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Elucidation of structure-activity relationship of humulanolides and identification of humulanolide analog as a novel HSP90 inhibitor.
Saegusa, Junya; Osada, Yoshiyuki; Miura, Kazuki; Sasazawa, Yukiko; Ogura, Akihiro; Takao, Ken-Ichi; Simizu, Siro.
Afiliação
  • Saegusa J; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
  • Osada Y; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
  • Miura K; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
  • Sasazawa Y; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
  • Ogura A; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
  • Takao KI; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan.
  • Simizu S; Department of Applied Chemistry, Faculty of Science and Technology, Keio University, 3-14-1 Hiyoshi, Kohoku-ku, Yokohama 223-8522, Japan. Electronic address: simizu@applc.keio.ac.jp.
Bioorg Med Chem Lett ; 60: 128589, 2022 03 15.
Article em En | MEDLINE | ID: mdl-35093502
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Proteínas de Choque Térmico HSP90 / Asteraceae / Antineoplásicos Fitogênicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Produtos Biológicos / Proteínas de Choque Térmico HSP90 / Asteraceae / Antineoplásicos Fitogênicos Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Bioorg Med Chem Lett Ano de publicação: 2022 Tipo de documento: Article