Successful Treatment of a 92-Year-Old Classic Kaposi's Sarcoma Man With Ultra-Low Dose Oral Etoposide.
J Oncol Pharm Pract
; 28(7): 1671-1673, 2022 Oct.
Article
em En
| MEDLINE
| ID: mdl-35105224
ABSTRACT
INTRODUCTION:
Because classic Kaposi's sarcoma (CKS) is currently regarded as a low-grade vascular malignancy, it has been usually known as indolent clinical course. The slow-growing neoplasms are usually asymptomatic and rarely systematically progressive. Although CKS is a chronic disease which is rarely life-threatening, systemic therapy may be necessary in some patients with symptomatic skin or visceral involvement. CASE REPORT In this report, we presented a 92-year-old CKS man with widespread and symptomatic skin lesions. MANAGEMENT ANDOUTCOME:
Patient was treated successfully with ultra-low dose oral etoposide; 50â mg/day for 7 days. Cycles were repeated in every 21 days. There was a dramatic regression in all lesions at the end of treatment; only skin colorations were persisted instead of palpable nodular lesions. Moreover, no serious hematological and non-hematological adverse events were observed.DISCUSSION:
Fragile advanced CKS patients with advanced age and/or comorbitidies need to be considered to optimize outcomes. Treatment with single-agent oral chemotherapy, oral ultra-low dose etoposide, may be one of the effective treatment styles.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Sarcoma de Kaposi
/
Neoplasias Cutâneas
Limite:
Aged80
/
Humans
/
Male
Idioma:
En
Revista:
J Oncol Pharm Pract
Ano de publicação:
2022
Tipo de documento:
Article