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Interruption of bile acid uptake by hepatocytes after acetaminophen overdose ameliorates hepatotoxicity.
Ghallab, Ahmed; Hassan, Reham; Hofmann, Ute; Friebel, Adrian; Hobloss, Zaynab; Brackhagen, Lisa; Begher-Tibbe, Brigitte; Myllys, Maiju; Reinders, Joerg; Overbeck, Nina; Sezgin, Selahaddin; Zühlke, Sebastian; Seddek, Abdel-Latif; Murad, Walaa; Brecklinghaus, Tim; Kappenberg, Franziska; Rahnenführer, Jörg; González, Daniela; Goldring, Christopher; Copple, Ian M; Marchan, Rosemarie; Longerich, Thomas; Vucur, Mihael; Luedde, Tom; Urban, Stephan; Canbay, Ali; Schreiter, Thomas; Trauner, Michael; Akakpo, Jephte Y; Olyaee, Mojtaba; Curry, Steven C; Sowa, Jan-Peter; Jaeschke, Hartmut; Hoehme, Stefan; Hengstler, Jan G.
Afiliação
  • Ghallab A; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University, 83523, Qena, Egypt. Electronic address: ghallab@ifado.de.
  • Hassan R; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University, 83523, Qena, Egypt.
  • Hofmann U; Dr. Margarete Fischer-Bosch Institute of Clinical Pharmacology and University of Tübingen, Auerbachstr. 112, 70376 Stuttgart, Germany.
  • Friebel A; Institute of Computer Science & Saxonian Incubator for Clinical Research (SIKT), University of Leipzig, Haertelstraße 16-18, 04107, Leipzig, Germany.
  • Hobloss Z; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Brackhagen L; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Begher-Tibbe B; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Myllys M; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Reinders J; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Overbeck N; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Sezgin S; Faculty of Chemistry and Chemical Biology, TU Dortmund, Dortmund, Germany.
  • Zühlke S; Center for Mass Spectrometry (CMS), Faculty of Chemistry and Chemical Biology, TU Dortmund University, Dortmund, Germany.
  • Seddek AL; Department of Forensic Medicine and Toxicology, Faculty of Veterinary Medicine, South Valley University, 83523, Qena, Egypt.
  • Murad W; Histology Department, Faculty of Medicine, South Valley University, 83523 Qena, Egypt.
  • Brecklinghaus T; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Kappenberg F; Department of Statistics, TU Dortmund University, 44227, Dortmund, Germany.
  • Rahnenführer J; Department of Statistics, TU Dortmund University, 44227, Dortmund, Germany.
  • González D; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Goldring C; Department of Pharmacology and Therapeutics, MRC Centre of Drug Safety Science, University of Liverpool, The Sherrington Building, Ashton Street, Liverpool, L69 3GE, UK.
  • Copple IM; Department of Pharmacology and Therapeutics, MRC Centre of Drug Safety Science, University of Liverpool, The Sherrington Building, Ashton Street, Liverpool, L69 3GE, UK.
  • Marchan R; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany.
  • Longerich T; Translational Gastrointestinal Pathology, Institute of Pathology, University Hospital Heidelberg, Heidelberg, Germany.
  • Vucur M; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty at Heinrich-Heine-University, Dusseldorf, Germany.
  • Luedde T; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty at Heinrich-Heine-University, Dusseldorf, Germany.
  • Urban S; Department of Infectious Diseases, Molecular Virology, University Hospital Heidelberg, Heidelberg, Germany; German Center for Infection Research, Heidelberg University, Heidelberg, Germany.
  • Canbay A; Department of Medicine, Ruhr University Bochum, University Hospital Knappschaftskrankenhaus Bochum, 44892 Bochum, Germany.
  • Schreiter T; Department of Medicine, Ruhr University Bochum, University Hospital Knappschaftskrankenhaus Bochum, 44892 Bochum, Germany.
  • Trauner M; Hans Popper Laboratory of Molecular Hepatology, Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria.
  • Akakpo JY; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS, USA.
  • Olyaee M; Division of Gastroenterology and Hepatology, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
  • Curry SC; Division of Clinical Data Analytics and Decision Support, Division of Medical Toxicology and Precision Medicine, Department of Medicine, University of Arizona College of Medicine-Phoenix, Phoenix, AZ, USA.
  • Sowa JP; Department of Medicine, Ruhr University Bochum, University Hospital Knappschaftskrankenhaus Bochum, 44892 Bochum, Germany.
  • Jaeschke H; Department of Pharmacology, Toxicology, and Therapeutics, University of Kansas Medical Center, Kansas City, KS, USA.
  • Hoehme S; Institute of Computer Science & Saxonian Incubator for Clinical Research (SIKT), University of Leipzig, Haertelstraße 16-18, 04107, Leipzig, Germany.
  • Hengstler JG; Leibniz Research Centre for Working Environment and Human Factors, Technical University Dortmund, Ardeystr. 67, 44139, Dortmund, Germany. Electronic address: hengstler@ifado.de.
J Hepatol ; 77(1): 71-83, 2022 07.
Article em En | MEDLINE | ID: mdl-35131407
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Doença Hepática Induzida por Substâncias e Drogas / Overdose de Drogas Limite: Animals / Humans Idioma: En Revista: J Hepatol Ano de publicação: 2022 Tipo de documento: Article
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 4_TD / 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Doença Hepática Induzida por Substâncias e Drogas / Overdose de Drogas Limite: Animals / Humans Idioma: En Revista: J Hepatol Ano de publicação: 2022 Tipo de documento: Article