Synthesis of Biotinylated PAMAM G3 Dendrimers Substituted with <i>R</i>-Glycidol and Celecoxib/Simvastatin as Repurposed Drugs and Evaluation of Their Increased Additive Cytotoxicity for Cancer Cell Lines.

Wróbel, Konrad; Wolowiec, Stanislaw; Markowicz, Joanna; Walajtys-Rode, Elzbieta; Uram, Lukasz

Synthesis of Biotinylated PAMAM G3 Dendrimers Substituted with R-Glycidol and Celecoxib/Simvastatin as Repurposed Drugs and Evaluation of Their Increased Additive Cytotoxicity for Cancer Cell Lines.

Wróbel, Konrad; Wolowiec, Stanislaw; Markowicz, Joanna; Walajtys-Rode, Elzbieta; Uram, Lukasz.

Afiliação

Wróbel K; Medical College, Rzeszów University, 1a Warzywna Str., 35-310 Rzeszów, Poland.
Wolowiec S; Medical College, Rzeszów University, 1a Warzywna Str., 35-310 Rzeszów, Poland.
Markowicz J; Faculty of Chemistry, Department of Inorganic and Analytical Chemistry, Rzeszów University of Technology, 6 Powstancow Warszawy Ave., 35-959 Rzeszów, Poland.
Walajtys-Rode E; Faculty of Chemistry, Warsaw University of Technology, 75 Koszykowa Str., 00-664 Warsaw, Poland.
Uram L; Faculty of Chemistry, Department of Inorganic and Analytical Chemistry, Rzeszów University of Technology, 6 Powstancow Warszawy Ave., 35-959 Rzeszów, Poland.

Cancers (Basel) ; 14(3)2022 Jan 29.

Article em En | MEDLINE | ID: mdl-35158983

Palavras-chave

R-glycidylated PAMAM G3 dendrimers; biotinylated; celecoxib; cytotoxicity; drug delivery system; human glioblastoma (U-118 MG); human squamous carcinoma (SCC-15-15); molecular size; normal human fibroblasts (BJ); simvastatin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cancers (Basel) Ano de publicação: 2022 Tipo de documento: Article

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Cancers (Basel) Ano de publicação: 2022 Tipo de documento: Article