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APP and DYRK1A regulate axonal and synaptic vesicle protein networks and mediate Alzheimer's pathology in trisomy 21 neurons.
Wu, Chun-I; Vinton, Elizabeth A; Pearse, Richard V; Heo, Keunjung; Aylward, Aimee J; Hsieh, Yi-Chen; Bi, Yan; Adeleye, Sopefoluwa; Fancher, Seeley; Duong, Duc M; Seyfried, Nicholas T; Schwarz, Thomas L; Young-Pearse, Tracy L.
Afiliação
  • Wu CI; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • Vinton EA; Harvard Medical School, Boston, MA, USA.
  • Pearse RV; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • Heo K; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • Aylward AJ; Harvard Medical School, Boston, MA, USA.
  • Hsieh YC; Harvard Medical School, Boston, MA, USA.
  • Bi Y; Kirby Neurobiology Center, Boston Children's Hospital, Boston, MA, USA.
  • Adeleye S; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • Fancher S; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • Duong DM; Harvard Medical School, Boston, MA, USA.
  • Seyfried NT; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • Schwarz TL; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
  • Young-Pearse TL; Ann Romney Center for Neurologic Diseases, Brigham and Women's Hospital, Boston, MA, USA.
Mol Psychiatry ; 27(4): 1970-1989, 2022 04.
Article em En | MEDLINE | ID: mdl-35194165
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Proteínas Serina-Treonina Quinases / Síndrome de Down / Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Psychiatry Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Tirosina Quinases / Proteínas Serina-Treonina Quinases / Síndrome de Down / Células-Tronco Pluripotentes Induzidas / Doença de Alzheimer Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Psychiatry Ano de publicação: 2022 Tipo de documento: Article