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CeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL): study protocol of a phase III, randomized, quadruple-blinded, placebo-controlled, Dutch multicenter trial.
Stegeman, Raymond; Nijman, Maaike; Breur, Johannes M P J; Groenendaal, Floris; Haas, Felix; Derks, Jan B; Nijman, Joppe; van Beynum, Ingrid M; Taverne, Yannick J H J; Bogers, Ad J J C; Helbing, Willem A; de Boode, Willem P; Bos, Arend F; Berger, Rolf M F; Accord, Ryan E; Roes, Kit C B; de Wit, G Ardine; Jansen, Nicolaas J G; Benders, Manon J N L.
Afiliação
  • Stegeman R; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center (UMC) Utrecht, Utrecht University, KE 04.123.1, PO Box 85909, 3508, AB, Utrecht, The Netherlands.
  • Nijman M; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Breur JMPJ; Department of Pediatric Intensive Care, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Groenendaal F; Congenital Cardiothoracic Surgery, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Haas F; Utrecht Brain Center, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Derks JB; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center (UMC) Utrecht, Utrecht University, KE 04.123.1, PO Box 85909, 3508, AB, Utrecht, The Netherlands.
  • Nijman J; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • van Beynum IM; Utrecht Brain Center, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Taverne YJHJ; Department of Pediatric Cardiology, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Bogers AJJC; Department of Neonatology, Wilhelmina Children's Hospital, University Medical Center (UMC) Utrecht, Utrecht University, KE 04.123.1, PO Box 85909, 3508, AB, Utrecht, The Netherlands.
  • Helbing WA; Utrecht Brain Center, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • de Boode WP; Congenital Cardiothoracic Surgery, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Bos AF; Department of Obstetrics, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Berger RMF; Department of Pediatric Intensive Care, Wilhelmina Children's Hospital, UMC Utrecht, Utrecht University, Utrecht, The Netherlands.
  • Accord RE; Department of Pediatrics, Division of Pediatric Cardiology, Academic Center for Congenital Heart Disease, Erasmus Medical Center (MC) - Sophia Children's Hospital, Rotterdam, The Netherlands.
  • Roes KCB; Department of Cardiothoracic Surgery, Erasmus MC, Erasmus University Rotterdam, Rotterdam, The Netherlands.
  • de Wit GA; Department of Cardiothoracic Surgery, Erasmus MC, Erasmus University Rotterdam, Rotterdam, The Netherlands.
  • Jansen NJG; Department of Pediatrics, Division of Pediatric Cardiology, Academic Center for Congenital Heart Disease, Erasmus Medical Center (MC) - Sophia Children's Hospital, Rotterdam, The Netherlands.
  • Benders MJNL; Department of Pediatrics, Division of Pediatric Cardiology, Academic Center for Congenital Heart Disease, Radboudumc - Amalia Children's Hospital, Nijmegen, The Netherlands.
Trials ; 23(1): 174, 2022 Feb 23.
Article em En | MEDLINE | ID: mdl-35197082
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles / 7_ODS3_muertes_prevenibles_nacidos_ninos Base de dados: MEDLINE Assunto principal: Alopurinol / Substâncias Protetoras / Cardiopatias Congênitas Tipo de estudo: Clinical_trials Aspecto: Patient_preference Limite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Trials Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 / 2_ODS3 / 6_ODS3_enfermedades_notrasmisibles / 7_ODS3_muertes_prevenibles_nacidos_ninos Base de dados: MEDLINE Assunto principal: Alopurinol / Substâncias Protetoras / Cardiopatias Congênitas Tipo de estudo: Clinical_trials Aspecto: Patient_preference Limite: Female / Humans / Newborn / Pregnancy Idioma: En Revista: Trials Ano de publicação: 2022 Tipo de documento: Article