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The Pathological G51D Mutation in Alpha-Synuclein Oligomers Confers Distinct Structural Attributes and Cellular Toxicity.
Xu, Catherine K; Castellana-Cruz, Marta; Chen, Serene W; Du, Zhen; Meisl, Georg; Levin, Aviad; Mannini, Benedetta; Itzhaki, Laura S; Knowles, Tuomas P J; Dobson, Christopher M; Cremades, Nunilo; Kumita, Janet R.
Afiliação
  • Xu CK; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Castellana-Cruz M; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Chen SW; Department of Life Sciences, South Kensington Campus, Imperial College London, London SW7 2AZ, UK.
  • Du Z; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK.
  • Meisl G; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Levin A; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Mannini B; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Itzhaki LS; Department of Pharmacology, University of Cambridge, Tennis Court Road, Cambridge CB2 1PD, UK.
  • Knowles TPJ; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Dobson CM; Cavendish Laboratory, Department of Physics, University of Cambridge, JJ Thomson Avenue, Cambridge CB3 0HE, UK.
  • Cremades N; Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, UK.
  • Kumita JR; Institute for Biocomputation and Physics of Complex Systems (BIFI), University of Zaragoza, Mariano Esquillor, Edificio I+D+I, 50018 Zaragoza, Spain.
Molecules ; 27(4)2022 Feb 15.
Article em En | MEDLINE | ID: mdl-35209093
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alfa-Sinucleína / Multimerização Proteica / Agregação Patológica de Proteínas / Mutação Limite: Humans Idioma: En Revista: Molecules Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alfa-Sinucleína / Multimerização Proteica / Agregação Patológica de Proteínas / Mutação Limite: Humans Idioma: En Revista: Molecules Ano de publicação: 2022 Tipo de documento: Article