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Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay.
Narayanan, Anoop; Narwal, Manju; Majowicz, Sydney A; Varricchio, Carmine; Toner, Shay A; Ballatore, Carlo; Brancale, Andrea; Murakami, Katsuhiko S; Jose, Joyce.
Afiliação
  • Narayanan A; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA.
  • Narwal M; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA.
  • Majowicz SA; Huck Institutes of the Life Sciences, The Pennsylvania State University, University Park, PA, USA.
  • Varricchio C; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, CF10 3NB, Cardiff, UK.
  • Toner SA; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA.
  • Ballatore C; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093, USA.
  • Brancale A; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, King Edward VII Avenue, CF10 3NB, Cardiff, UK.
  • Murakami KS; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA.
  • Jose J; Department of Biochemistry and Molecular Biology, The Pennsylvania State University, University Park, PA, USA. jxj321@psu.edu.
Commun Biol ; 5(1): 169, 2022 02 25.
Article em En | MEDLINE | ID: mdl-35217718

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Avaliação Pré-Clínica de Medicamentos / Inibidores de Protease Viral / Proteases 3C de Coronavírus / Proteases Semelhantes à Papaína de Coronavírus / SARS-CoV-2 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Commun Biol Ano de publicação: 2022 Tipo de documento: Article

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Avaliação Pré-Clínica de Medicamentos / Inibidores de Protease Viral / Proteases 3C de Coronavírus / Proteases Semelhantes à Papaína de Coronavírus / SARS-CoV-2 Tipo de estudo: Diagnostic_studies Limite: Humans Idioma: En Revista: Commun Biol Ano de publicação: 2022 Tipo de documento: Article