A new link between apoptosis induced by the metformin derivative HL156A and autophagy in oral squamous cell carcinoma.

Nguyen, Manh Tuong; Choe, Han-Cheol; Kim, Byung-Hoon; Ahn, Sang-Gun

Nguyen, Manh Tuong; Choe, Han-Cheol; Kim, Byung-Hoon; Ahn, Sang-Gun.

Afiliação

Nguyen MT; Department of Pathology, School of Dentistry, Chosun University, Gwangju, 61452, Republic of Korea.
Choe HC; Department of Dental Materials & Research Center of Nano-Interface Activation for Biomaterials, College of Dentistry, Chosun University, Gwangju, 61452, Republic of Korea.
Kim BH; Department of Dental Materials & Research Center of Nano-Interface Activation for Biomaterials, College of Dentistry, Chosun University, Gwangju, 61452, Republic of Korea.
Ahn SG; Department of Pathology, School of Dentistry, Chosun University, Gwangju, 61452, Republic of Korea. Electronic address: ahnsg@chosun.ac.kr.

Eur J Pharmacol ; 920: 174859, 2022 Apr 05.

Article em En | MEDLINE | ID: mdl-35219727

Assuntos

Carcinoma de Células Escamosas; Neoplasias de Cabeça e Pescoço; Metformina; Neoplasias Bucais; Animais; Apoptose; Autofagia; Carcinoma de Células Escamosas/patologia; Linhagem Celular Tumoral; Proliferação de Células; Guanidinas; Humanos; Metformina/farmacologia; Metformina/uso terapêutico; Camundongos; Neoplasias Bucais/patologia; Pirrolidinas; Carcinoma de Células Escamosas de Cabeça e Pescoço/tratamento farmacológico; Ensaios Antitumorais Modelo de Xenoenxerto

Palavras-chave

Apoptosis; Autophagy; Epithelial-mesenchymal transition; HL156A; Metformin derivative; Oral squamous cell carcinoma

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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 6_ODS3_enfermedades_notrasmisibles Base de dados: MEDLINE Assunto principal: Neoplasias Bucais / Carcinoma de Células Escamosas / Neoplasias de Cabeça e Pescoço / Metformina Limite: Animals / Humans Idioma: En Revista: Eur J Pharmacol Ano de publicação: 2022 Tipo de documento: Article

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