[Endocrine side effects of radiation therapy: Diagnosis, prevention, and treatment]. / Effets secondaires endocriniens de la radiothérapie : diagnostic, prévention et traitements.
Cancer Radiother
; 26(8): 1078-1089, 2022 Nov.
Article
em Fr
| MEDLINE
| ID: mdl-35260341
Endocrine complications after radiotherapy are usually delayed and require prolonged follow-up by the radiation oncologist. Endocrine glands are dispersed throughout the body and can be included in the radiation field of several tumors. As the symptomatology can sometimes be insidious and non-specific, their screening is based on a directed clinical examination but also on systematic hormonal assays. The thyroid gland is particularly radiosensitive, and hypothyroidism is generally observed for doses of more than 30Gy. After cervical irradiation, it is recommended to perform a TSH assay every 6 to 12months. The risk of secondary thyroid cancer only concerns children and exists even at low doses, systematic screening is required. The risk of pituitary insufficiency is dose-dependent, with different sensitivity for each axis. In children, the main concern is the early detection of somatotropic insufficiency in order to prevent the risk of short stature. Reproductive function can be impaired after receiving 4-6Gy requiring fertility preservation. Endocrine side effects can be treated to improve quality of life; therefore, we propose several approaches to be followed in order to promote screening and treatment.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Contexto em Saúde:
1_ASSA2030
/
2_ODS3
Base de dados:
MEDLINE
Assunto principal:
Neoplasias da Glândula Tireoide
/
Hipotireoidismo
Tipo de estudo:
Diagnostic_studies
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Etiology_studies
/
Screening_studies
Aspecto:
Patient_preference
Limite:
Child
/
Humans
Idioma:
Fr
Revista:
Cancer Radiother
Ano de publicação:
2022
Tipo de documento:
Article