LECT2 Ameliorates Blood-Retinal Barrier Impairment Secondary to Diabetes Via Activation of the Tie2/Akt/mTOR Signaling Pathway.

Qin, Yuan-Jun; Xiao, Ke; Zhong, Zheng; Zhao, Yin; Yu, Tian; Sun, Xu-Fang

Qin, Yuan-Jun; Xiao, Ke; Zhong, Zheng; Zhao, Yin; Yu, Tian; Sun, Xu-Fang.

Afiliação

Qin YJ; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People's Republic of China.
Xiao K; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People's Republic of China.
Zhong Z; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People's Republic of China.
Zhao Y; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People's Republic of China.
Yu T; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People's Republic of China.
Sun XF; Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei Province, People's Republic of China.

Invest Ophthalmol Vis Sci ; 63(3): 7, 2022 03 02.

Article em En | MEDLINE | ID: mdl-35262733

Assuntos

Barreira Hematorretiniana; Diabetes Mellitus; Retinopatia Diabética; Peptídeos e Proteínas de Sinalização Intercelular; Animais; Diabetes Mellitus/metabolismo; Retinopatia Diabética/tratamento farmacológico; Retinopatia Diabética/metabolismo; Glucose/farmacologia; Células Endoteliais da Veia Umbilical Humana/metabolismo; Humanos; Peptídeos e Proteínas de Sinalização Intercelular/farmacologia; Camundongos; Proteínas Proto-Oncogênicas c-akt/metabolismo; Receptor TIE-2/metabolismo; Proteínas Recombinantes/farmacologia; Vasos Retinianos/metabolismo; Transdução de Sinais; Serina-Treonina Quinases TOR/metabolismo

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Barreira Hematorretiniana / Peptídeos e Proteínas de Sinalização Intercelular / Diabetes Mellitus / Retinopatia Diabética Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Invest Ophthalmol Vis Sci Ano de publicação: 2022 Tipo de documento: Article

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