Simple and sensitive method for the determination of methylmercury in hair using thin-layer chromatography with thermal decomposition gold amalgamation atomic absorption spectrophotometry.
Anal Sci
; 38(1): 215-221, 2022 01.
Article
em En
| MEDLINE
| ID: mdl-35287225
ABSTRACT
An improved method is described for the determination of methylmercury (MeHg) in human hair that is based on thin-layer chromatography and thermal decomposition gold amalgamation atomic absorption spectrophotometry. The dithizone extraction and application procedure of this technique were optimized, thus improving its sensitivity and robustness and enabling the use of less toxic solvents than other approaches. The limit of detection was 0.18 ng MeHg (as Hg), corresponding to 0.018 mg MeHg kg-1 of hair relative to a 10 mg sample. This method is appropriate for detecting MeHg in hair at the approximate reference dose level established by the United States Environmental Protection Agency.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Compostos de Metilmercúrio
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
País/Região como assunto:
America do norte
Idioma:
En
Revista:
Anal Sci
Ano de publicação:
2022
Tipo de documento:
Article