Cleavage-defective Topoisomerase I mutants sharply increase G-quadruplex-associated genomic instability.

Berroyer, Alexandra; Bacolla, Albino; Tainer, John A; Kim, Nayun

Berroyer, Alexandra; Bacolla, Albino; Tainer, John A; Kim, Nayun.

Afiliação

Berroyer A; Department of Microbiology and Molecular Genetics, University of Texas Health Science Center at Houston, Houston, TX 77030, USA.
Bacolla A; MD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, TX, 77030, USA.
Tainer JA; Department of Molecular and Cellular Oncology, University of Texas M.D. Anderson Cancer Center, Houston, TX 77030, USA.
Kim N; MD Anderson Cancer Center UT Health Graduate School of Biomedical Sciences, Houston, TX, 77030, USA.

Microb Cell ; 9(3): 52-68, 2022 Mar 07.

Article em En | MEDLINE | ID: mdl-35291312

Palavras-chave

G-quadruplex; Topoisomerase; genome instability; recombination; transcription

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Risk_factors_studies Idioma: En Revista: Microb Cell Ano de publicação: 2022 Tipo de documento: Article

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