Exosomal microRNA-140-3p from human umbilical cord mesenchymal stem cells attenuates joint injury of rats with rheumatoid arthritis by silencing SGK1.

Huang, Yijiang; Chen, Liang; Chen, Daosen; Fan, Pei; Yu, Huachen

Huang, Yijiang; Chen, Liang; Chen, Daosen; Fan, Pei; Yu, Huachen.

Afiliação

Huang Y; Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 West College Road, Wenzhou, 325000, China.
Chen L; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou, 325000, China.
Chen D; Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 West College Road, Wenzhou, 325000, China.
Fan P; Key Laboratory of Orthopaedics of Zhejiang Province, Wenzhou, 325000, China.
Yu H; Department of Orthopaedic, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 West College Road, Wenzhou, 325000, China.

Mol Med ; 28(1): 36, 2022 03 18.

Article em En | MEDLINE | ID: mdl-35303795

Assuntos

Artrite Reumatoide; Exossomos; Células-Tronco Mesenquimais; MicroRNAs; Animais; Artrite Reumatoide/genética; Artrite Reumatoide/terapia; Proliferação de Células; Fibrose; Humanos; Inflamação/patologia; MicroRNAs/genética; Ratos; Cordão Umbilical/patologia

Palavras-chave

Exosome; Joint injury; MicroRNA-140-3p; Rat; Rheumatoid arthritis; Serum-and glucocorticoid-inducible kinase 1

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Artrite Reumatoide / MicroRNAs / Exossomos / Células-Tronco Mesenquimais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Mol Med Ano de publicação: 2022 Tipo de documento: Article

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