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Site-Selective Antibody-Drug Conjugation by a Proximity-Driven S to N Acyl Transfer Reaction on a Therapeutic Antibody.
Lee, TaeJin; Kim, Ju Hwan; Kwon, Se Jeong; Seo, Jin Woo; Park, Sun Hee; Kim, Jinyoung; Jin, Jonghwa; Hong, Ji Hye; Kang, Hyo Jin; Sharma, Chiranjeev; Choi, Ji Hoon; Chung, Sang J.
Afiliação
  • Lee T; School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangangu, Suwon 16419, Republic of Korea.
  • Kim JH; AbTis Company Ltd., A-815, Suwon Venture Valley II, 142-10, Saneop-ro156beon-gil, Gwonseon-gu, Suwon, Gyeonggi-do 16648, Republic of Korea.
  • Kwon SJ; AbTis Company Ltd., A-815, Suwon Venture Valley II, 142-10, Saneop-ro156beon-gil, Gwonseon-gu, Suwon, Gyeonggi-do 16648, Republic of Korea.
  • Seo JW; School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangangu, Suwon 16419, Republic of Korea.
  • Park SH; AbTis Company Ltd., A-815, Suwon Venture Valley II, 142-10, Saneop-ro156beon-gil, Gwonseon-gu, Suwon, Gyeonggi-do 16648, Republic of Korea.
  • Kim J; School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangangu, Suwon 16419, Republic of Korea.
  • Jin J; AbTis Company Ltd., A-815, Suwon Venture Valley II, 142-10, Saneop-ro156beon-gil, Gwonseon-gu, Suwon, Gyeonggi-do 16648, Republic of Korea.
  • Hong JH; School of Pharmacy, Sungkyunkwan University, 2066 Seoburo, Jangangu, Suwon 16419, Republic of Korea.
  • Kang HJ; AbTis Company Ltd., A-815, Suwon Venture Valley II, 142-10, Saneop-ro156beon-gil, Gwonseon-gu, Suwon, Gyeonggi-do 16648, Republic of Korea.
  • Sharma C; Biocenter, Gyeonggido Business and Science Accelerator, Suwon 16229, Republic of Korea.
  • Choi JH; Department of Convergence Technical Support, New Drug Development Center, 123 Osongsaengmyeng-ro, Cheongju, Chungbuk 28160, Republic of Korea.
  • Chung SJ; Department of Convergence Technical Support, New Drug Development Center, 123 Osongsaengmyeng-ro, Cheongju, Chungbuk 28160, Republic of Korea.
J Med Chem ; 65(7): 5751-5759, 2022 04 14.
Article em En | MEDLINE | ID: mdl-35319890
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoconjugados Idioma: En Revista: J Med Chem Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Imunoconjugados Idioma: En Revista: J Med Chem Ano de publicação: 2022 Tipo de documento: Article