Bee Venom and Its Major Component Melittin Attenuated <i>Cutibacterium acnes</i>- and IGF-1-Induced Acne Vulgaris via Inactivation of Akt/mTOR/SREBP Signaling Pathway.

Gu, Hyemin; An, Hyun-Jin; Gwon, Mi-Gyeong; Bae, Seongjae; Leem, Jaechan; Lee, Sun-Jae; Han, Sang-Mi; Zouboulis, Christos C; Park, Kwan-Kyu

Bee Venom and Its Major Component Melittin Attenuated Cutibacterium acnes- and IGF-1-Induced Acne Vulgaris via Inactivation of Akt/mTOR/SREBP Signaling Pathway.

Gu, Hyemin; An, Hyun-Jin; Gwon, Mi-Gyeong; Bae, Seongjae; Leem, Jaechan; Lee, Sun-Jae; Han, Sang-Mi; Zouboulis, Christos C; Park, Kwan-Kyu.

Afiliação

Gu H; Department of Pathology, School of Medicine, Catholic University of Daegu, Gyeongsan 42472, Korea.
An HJ; Department of Pathology, School of Medicine, Catholic University of Daegu, Gyeongsan 42472, Korea.
Gwon MG; Department of Pathology, School of Medicine, Catholic University of Daegu, Gyeongsan 42472, Korea.
Bae S; Department of Pathology, School of Medicine, Catholic University of Daegu, Gyeongsan 42472, Korea.
Leem J; Department of Immunology, School of Medicine, Catholic University of Daegu, Gyeongsan 42472, Korea.
Lee SJ; Department of Pathology, School of Medicine, Catholic University of Daegu, Gyeongsan 42472, Korea.
Han SM; Department of Agricultural Biology, National Academy of Agricultural Science, RDA, Wanju 54875, Korea.
Zouboulis CC; Departments of Dermatology, Venereology, Allergology and Immunology, Dessau Medical Center, Brandenburg Medical School Theodor Fontane, Faculty of Health Sciences Brandenburg, Auenweg 38, 06847 Dessau, Germany.
Park KK; Department of Pathology, School of Medicine, Catholic University of Daegu, Gyeongsan 42472, Korea.

Int J Mol Sci ; 23(6)2022 Mar 15.

Article em En | MEDLINE | ID: mdl-35328573

Assuntos

Acne Vulgar; Venenos de Abelha; Acne Vulgar/tratamento farmacológico; Anti-Inflamatórios/farmacologia; Venenos de Abelha/farmacologia; Humanos; Fator de Crescimento Insulin-Like I/farmacologia; Meliteno/farmacologia; Propionibacterium acnes; Proteínas Proto-Oncogênicas c-akt/metabolismo; Transdução de Sinais; Sirolimo/farmacologia; Proteína de Ligação a Elemento Regulador de Esterol 1/metabolismo; Serina-Treonina Quinases TOR/metabolismo

Palavras-chave

C. acnes; IGF-1; bee venom; lipogenesis; melittin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Venenos de Abelha / Acne Vulgar Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Int J Mol Sci Ano de publicação: 2022 Tipo de documento: Article

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