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A kinase-dead Csf1r mutation associated with adult-onset leukoencephalopathy has a dominant inhibitory impact on CSF1R signalling.
Stables, Jennifer; Green, Emma K; Sehgal, Anuj; Patkar, Omkar L; Keshvari, Sahar; Taylor, Isis; Ashcroft, Maisie E; Grabert, Kathleen; Wollscheid-Lengeling, Evi; Szymkowiak, Stefan; McColl, Barry W; Adamson, Antony; Humphreys, Neil E; Mueller, Werner; Starobova, Hana; Vetter, Irina; Shabestari, Sepideh Kiani; Blurton-Jones, Matthew M; Summers, Kim M; Irvine, Katharine M; Pridans, Clare; Hume, David A.
Afiliação
  • Stables J; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Qld 4102, Australia.
  • Green EK; Centre for Inflammation Research and Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH16 4TJ, UK.
  • Sehgal A; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Qld 4102, Australia.
  • Patkar OL; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Qld 4102, Australia.
  • Keshvari S; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Qld 4102, Australia.
  • Taylor I; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Qld 4102, Australia.
  • Ashcroft ME; Centre for Inflammation Research and Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH16 4TJ, UK.
  • Grabert K; Toxicology Unit, Institute of Environmental Medicine, Karolinska Institutet, Stockholm 171 77, Sweden.
  • Wollscheid-Lengeling E; Luxembourg Centre for Systems Biomedicine, Université du Luxembourg, Belvaux, L-4401, Luxembourg.
  • Szymkowiak S; UK Dementia Research Institute, Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • McColl BW; UK Dementia Research Institute, Centre for Discovery Brain Sciences, University of Edinburgh, Edinburgh EH8 9XD, UK.
  • Adamson A; Genome Editing Unit, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Humphreys NE; Genome Editing Unit, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Mueller W; Genome Editing Unit, Faculty of Biology, Medicine and Health, University of Manchester, Manchester M13 9PT, UK.
  • Starobova H; Institute for Molecular Biosciences & School of Pharmacy, University of Queensland, Brisbane, Qld 4072, Australia.
  • Vetter I; Institute for Molecular Biosciences & School of Pharmacy, University of Queensland, Brisbane, Qld 4072, Australia.
  • Shabestari SK; Department of Neurobiology & Behavior, University of California, Irvine, CA 92697, USA.
  • Blurton-Jones MM; Department of Neurobiology & Behavior, University of California, Irvine, CA 92697, USA.
  • Summers KM; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Qld 4102, Australia.
  • Irvine KM; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Qld 4102, Australia.
  • Pridans C; Centre for Inflammation Research and Simons Initiative for the Developing Brain, University of Edinburgh, Edinburgh EH16 4TJ, UK.
  • Hume DA; Mater Research Institute-University of Queensland, Translational Research Institute, Brisbane, Qld 4102, Australia.
Development ; 149(8)2022 04 15.
Article em En | MEDLINE | ID: mdl-35333324
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Doenças Neurodegenerativas / Leucoencefalopatias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Development Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Receptores de Fator Estimulador das Colônias de Granulócitos e Macrófagos / Doenças Neurodegenerativas / Leucoencefalopatias Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Animals / Humans Idioma: En Revista: Development Ano de publicação: 2022 Tipo de documento: Article