Interleukin-17 programs liver progenitor cell transformation into cancer stem cells through miR-122 downregulation with increased risk of primary liver cancer initiation.

Gasmi, Imène; Machou, Camilia; Rodrigues, Aurélie; Brouillet, Arthur; Nguyen, Trung Cong; Rousseau, Benoit; Guillot, Adrien; Rodriguez, Christophe; Demontant, Vanessa; Ait-Ahmed, Yeni; Calderaro, Julien; Luciani, Alain; Pawlotsky, Jean-Michel; Lafdil, Fouad

Gasmi, Imène; Machou, Camilia; Rodrigues, Aurélie; Brouillet, Arthur; Nguyen, Trung Cong; Rousseau, Benoit; Guillot, Adrien; Rodriguez, Christophe; Demontant, Vanessa; Ait-Ahmed, Yeni; Calderaro, Julien; Luciani, Alain; Pawlotsky, Jean-Michel; Lafdil, Fouad.

Afiliação

Gasmi I; Université Paris-Est, UMR-S955, UPEC, F-94000, Créteil, France.
Machou C; INSERM, U955, F-94000, Créteil, France.
Rodrigues A; Université Paris-Est, UMR-S955, UPEC, F-94000, Créteil, France.
Brouillet A; INSERM, U955, F-94000, Créteil, France.
Nguyen TC; Université Paris-Est, UMR-S955, UPEC, F-94000, Créteil, France.
Rousseau B; INSERM, U955, F-94000, Créteil, France.
Guillot A; Université Paris-Est, UMR-S955, UPEC, F-94000, Créteil, France.
Rodriguez C; INSERM, U955, F-94000, Créteil, France.
Demontant V; Université Paris-Est, UMR-S955, UPEC, F-94000, Créteil, France.
Ait-Ahmed Y; INSERM, U955, F-94000, Créteil, France.
Calderaro J; Université Paris-Est, UMR-S955, UPEC, F-94000, Créteil, France.
Luciani A; INSERM, U955, F-94000, Créteil, France.
Pawlotsky JM; Université Paris-Est, UMR-S955, UPEC, F-94000, Créteil, France.
Lafdil F; INSERM, U955, F-94000, Créteil, France.

Int J Biol Sci ; 18(5): 1944-1960, 2022.

Article em En | MEDLINE | ID: mdl-35342340

Assuntos

Neoplasias Hepáticas; MicroRNAs; Animais; Linhagem Celular Tumoral; Transformação Celular Neoplásica/metabolismo; Regulação para Baixo; Inflamação/metabolismo; Interleucina-17/genética; Interleucina-17/metabolismo; Neoplasias Hepáticas/metabolismo; Camundongos; MicroRNAs/genética; MicroRNAs/metabolismo; Células-Tronco Neoplásicas/metabolismo

Palavras-chave

Interleukin-17; Liver progenitor cells; cancer stem cells; liver cancer, miR-122

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: MicroRNAs / Neoplasias Hepáticas Tipo de estudo: Etiology_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Int J Biol Sci Ano de publicação: 2022 Tipo de documento: Article

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