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Enhancement of prime editing via xrRNA motif-joined pegRNA.
Zhang, Guiquan; Liu, Yao; Huang, Shisheng; Qu, Shiyuan; Cheng, Daolin; Yao, Yuan; Ji, Quanjiang; Wang, Xiaolong; Huang, Xingxu; Liu, Jianghuai.
Afiliação
  • Zhang G; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center at Medical School of Nanjing University, 210061, Nanjing, China.
  • Liu Y; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, 712100, Yangling, Shaanxi, China.
  • Huang S; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, 100 Haike Rd., Pudong New Area, 201210, Shanghai, China.
  • Qu S; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, 100 Haike Rd., Pudong New Area, 201210, Shanghai, China.
  • Cheng D; State Key Laboratory of Pharmaceutical Biotechnology and MOE Key Laboratory of Model Animals for Disease Study, Model Animal Research Center at Medical School of Nanjing University, 210061, Nanjing, China.
  • Yao Y; Hangzhou Global Scientific and Technological Innovation Center, Zhejiang University, 311215, Hangzhou, China.
  • Ji Q; School of Physical Science and Technology, ShanghaiTech University, 100 Haike Rd., Pudong New Area, 201210, Shanghai, China.
  • Wang X; Key Laboratory of Animal Genetics, Breeding and Reproduction of Shaanxi Province, College of Animal Science and Technology, Northwest A&F University, 712100, Yangling, Shaanxi, China. xiaolongwang@nwafu.edu.cn.
  • Huang X; Gene Editing Center, School of Life Science and Technology, ShanghaiTech University, 100 Haike Rd., Pudong New Area, 201210, Shanghai, China. huangxx@shanghaitech.edu.cn.
  • Liu J; Zhejiang Laboratory, 311100, Hangzhou, China. huangxx@shanghaitech.edu.cn.
Nat Commun ; 13(1): 1856, 2022 04 06.
Article em En | MEDLINE | ID: mdl-35387980
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Idioma: En Revista: Nat Commun Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sistemas CRISPR-Cas / Edição de Genes Idioma: En Revista: Nat Commun Ano de publicação: 2022 Tipo de documento: Article