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Leveraging fine-mapping and multipopulation training data to improve cross-population polygenic risk scores.
Weissbrod, Omer; Kanai, Masahiro; Shi, Huwenbo; Gazal, Steven; Peyrot, Wouter J; Khera, Amit V; Okada, Yukinori; Martin, Alicia R; Finucane, Hilary K; Price, Alkes L.
Afiliação
  • Weissbrod O; Epidemiology Department, Harvard School of Public Health, Boston, MA, USA. oweissbrod@hsph.harvard.edu.
  • Kanai M; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
  • Shi H; Department of Statistical Genetics, Osaka University Graduate School of Medicine, Suita, Japan.
  • Gazal S; Epidemiology Department, Harvard School of Public Health, Boston, MA, USA.
  • Peyrot WJ; OMNI Bioinformatics, San Francisco, CA, USA.
  • Khera AV; Epidemiology Department, Harvard School of Public Health, Boston, MA, USA.
  • Okada Y; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
  • Martin AR; Epidemiology Department, Harvard School of Public Health, Boston, MA, USA.
  • Finucane HK; Department of Psychiatry, Amsterdam UMC, Vrije Universiteit, Amsterdam, the Netherlands.
  • Price AL; Broad Institute of MIT and Harvard, Cambridge, MA, USA.
Nat Genet ; 54(4): 450-458, 2022 04.
Article em En | MEDLINE | ID: mdl-35393596
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Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Herança Multifatorial / Estudo de Associação Genômica Ampla Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspecto: Equity_inequality Limite: Humans Idioma: En Revista: Nat Genet Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Contexto em Saúde: 1_ASSA2030 Base de dados: MEDLINE Assunto principal: Herança Multifatorial / Estudo de Associação Genômica Ampla Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Aspecto: Equity_inequality Limite: Humans Idioma: En Revista: Nat Genet Ano de publicação: 2022 Tipo de documento: Article