Emerging roles of DNA topoisomerases in the regulation of R-loops.

Patel, Parasvi S; Krishnan, Rehna; Hakem, Razqallah

Patel, Parasvi S; Krishnan, Rehna; Hakem, Razqallah.

Afiliação

Patel PS; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada.
Krishnan R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Hakem R; Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, M5G 1L7, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A8, Canada. Electronic address: rhakem@uhnresearch.ca.

Mutat Res Genet Toxicol Environ Mutagen ; 876-877: 503450, 2022.

Article em En | MEDLINE | ID: mdl-35483781

Assuntos

DNA Topoisomerases; Estruturas R-Loop; DNA/genética; Replicação do DNA; DNA Topoisomerases/genética; Instabilidade Genômica; Humanos

Palavras-chave

Cell cycle; DNA damage; DNA repair; DNA:RNA hybrids; Topoisomerases

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA Topoisomerases / Estruturas R-Loop Limite: Humans Idioma: En Revista: Mutat Res Genet Toxicol Environ Mutagen Ano de publicação: 2022 Tipo de documento: Article

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