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Allosteric coupling between transmembrane segment 4 and the selectivity filter of TALK1 potassium channels regulates their gating by extracellular pH.
Tsai, Wen-Hao; Grauffel, Cédric; Huang, Ming-Yueh; Postic, Sandra; Rupnik, Marjan Slak; Lim, Carmay; Yang, Shi-Bing.
Afiliação
  • Tsai WH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan International Graduate Program in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei, Taiwan.
  • Grauffel C; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
  • Huang MY; Institute of Statistical Science, Academia Sinica, Taipei, Taiwan.
  • Postic S; Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria.
  • Rupnik MS; Center for Physiology and Pharmacology, Medical University of Vienna, Vienna, Austria; Institute of Physiology, Faculty of Medicine, University of Maribor, Maribor, Slovenia; Alma Mater Europaea - European Center Maribor, Maribor, Slovenia.
  • Lim C; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.
  • Yang SB; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan; Taiwan International Graduate Program in Molecular Medicine, National Yang Ming Chiao Tung University and Academia Sinica, Taipei, Taiwan. Electronic address: sbyang@ibms.sinica.edu.tw.
J Biol Chem ; 298(6): 101998, 2022 06.
Article em En | MEDLINE | ID: mdl-35500647
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação do Canal Iônico / Canais de Potássio de Domínios Poros em Tandem Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Ativação do Canal Iônico / Canais de Potássio de Domínios Poros em Tandem Tipo de estudo: Prognostic_studies Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article