CRISPR-Cas9-mediated loss of function of ß-catenin attenuates intervertebral disc degeneration.

Fan, Yunshan; Zhao, Lan; Lai, Yumei; Lu, Ke; Huang, Jian

Fan, Yunshan; Zhao, Lan; Lai, Yumei; Lu, Ke; Huang, Jian.

Afiliação

Fan Y; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Zhao L; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Lai Y; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Lu K; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.
Huang J; Department of Orthopedic Surgery, Rush University Medical Center, Chicago, IL 60612, USA.

Mol Ther Nucleic Acids ; 28: 387-396, 2022 Jun 14.

Article em En | MEDLINE | ID: mdl-35505959

Palavras-chave

CRISPR-Cas9; MT: RNA/DNA Editing; adeno-associated virus; gene editing; intervertebral disc degeneration; notochordal cells; nucleus pulposus; ß-catenin

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mol Ther Nucleic Acids Ano de publicação: 2022 Tipo de documento: Article

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