Spitzoid proliferative nodules arising in a congenital melanocytic naevus: A case report with clinical, dermoscopic and histologic correlation.
Australas J Dermatol
; 63(3): e251-e254, 2022 Aug.
Article
em En
| MEDLINE
| ID: mdl-35510363
ABSTRACT
Proliferative nodules (PNs) are benign nodular proliferation of melanocytes occurring within congenital melanocytic naevi (CMN). Differential diagnosis between PN and melanoma is challenging for clinicians and pathologists. We describe the case of a 9-month-old boy who developed multiple nodules arising in a medium-sized CMN. Clinically, pink papules were observed, with dotted vessels on dermoscopy, suggesting spitzoid PN. On histopathological examination, the dermoscopic findings correlated with the vertical vessels of a spitzoid PN. Dermoscopy could be a useful tool to differentiate PN from melanoma. However, further studies describing the dermoscopic features of the different PN subtypes are needed. Histopathology remains the gold standard for definitive diagnosis aided by ancillary molecular tests such as fluorescence in situ hybridization or comparative genomic hybridization.
Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Cutâneas
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Nevo de Células Epitelioides e Fusiformes
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Melanoma
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Nevo Pigmentado
Tipo de estudo:
Diagnostic_studies
Limite:
Humans
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Infant
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Male
Idioma:
En
Revista:
Australas J Dermatol
Ano de publicação:
2022
Tipo de documento:
Article