Lipid-induced monokine cyclophilin-A promotes adipose tissue dysfunction implementing insulin resistance and type 2 diabetes in zebrafish and mice models of obesity.

Banerjee, Dipanjan; Patra, Debarun; Sinha, Archana; Roy, Soumyajit; Pant, Rajat; Sarmah, Raktim; Dutta, Rajdeep; Kanta Bhagabati, Sarada; Tikoo, Kulbhushan; Pal, Durba; Dasgupta, Suman

Banerjee, Dipanjan; Patra, Debarun; Sinha, Archana; Roy, Soumyajit; Pant, Rajat; Sarmah, Raktim; Dutta, Rajdeep; Kanta Bhagabati, Sarada; Tikoo, Kulbhushan; Pal, Durba; Dasgupta, Suman.

Afiliação

Banerjee D; Metabolic Disease Biology Laboratory, Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, 784028, Assam, India.
Patra D; Department of Biomedical Engineering, Indian Institute of Technology Ropar, Rupnagar, 140001, Punjab, India.
Sinha A; Metabolic Disease Biology Laboratory, Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, 784028, Assam, India.
Roy S; Department of Biomedical Engineering, Indian Institute of Technology Ropar, Rupnagar, 140001, Punjab, India.
Pant R; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, 160062, India.
Sarmah R; Department of Aquatic Environment Management, College of Fisheries, Assam Agricultural University, Nagaon, 782103, Assam, India.
Dutta R; Department of Aquatic Environment Management, College of Fisheries, Assam Agricultural University, Nagaon, 782103, Assam, India.
Kanta Bhagabati S; Department of Aquatic Environment Management, College of Fisheries, Assam Agricultural University, Nagaon, 782103, Assam, India.
Tikoo K; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research (NIPER), S.A.S. Nagar, Punjab, 160062, India.
Pal D; Department of Biomedical Engineering, Indian Institute of Technology Ropar, Rupnagar, 140001, Punjab, India. durba.pal@iitrpr.ac.in.
Dasgupta S; Metabolic Disease Biology Laboratory, Department of Molecular Biology and Biotechnology, Tezpur University, Tezpur, 784028, Assam, India. suman@tezu.ernet.in.

Cell Mol Life Sci ; 79(5): 282, 2022 May 05.

Article em En | MEDLINE | ID: mdl-35511344

Assuntos

Diabetes Mellitus Tipo 2; Resistência à Insulina; Tecido Adiposo/metabolismo; Animais; Ciclofilina A/genética; Ciclofilinas/metabolismo; Diabetes Mellitus Tipo 2/metabolismo; Inflamação/metabolismo; Resistência à Insulina/genética; Lipídeo A/metabolismo; Camundongos; Monocinas/metabolismo; Obesidade/metabolismo; Peixe-Zebra/genética

Palavras-chave

Adipogenesis; CD147; Cyclophilin-A; Inflammation; Insulin resistance; Monokine

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Resistência à Insulina / Diabetes Mellitus Tipo 2 Limite: Animals Idioma: En Revista: Cell Mol Life Sci Ano de publicação: 2022 Tipo de documento: Article

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