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Sinusoidal Uptake Determines the Hepatic Clearance of Pevonedistat (TAK-924) as Explained by Extended Clearance Model.
Sandoval, Philip; Chuang, Bei-Ching; Cohen, Lawrence; Yoneyama, Tomoki; Pusalkar, Sandeepraj; Yucha, Robert W; Chowdhury, Swapan K; Chothe, Paresh P.
Afiliação
  • Sandoval P; Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts.
  • Chuang BC; Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts.
  • Cohen L; Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts.
  • Yoneyama T; Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts.
  • Pusalkar S; Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts.
  • Yucha RW; Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts.
  • Chowdhury SK; Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts.
  • Chothe PP; Global Drug Metabolism and Pharmacokinetics, Takeda Development Center Americas, Inc. (TDCA), Lexington, Massachusetts paresh.chothe@takeda.com.
Drug Metab Dispos ; 50(7): 980-988, 2022 07.
Article em En | MEDLINE | ID: mdl-35545257
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Itraconazol / Citocromo P-450 CYP3A Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Drug Metab Dispos Ano de publicação: 2022 Tipo de documento: Article
Texto completo
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Itraconazol / Citocromo P-450 CYP3A Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Drug Metab Dispos Ano de publicação: 2022 Tipo de documento: Article