5-fluorouracil treatment of patient-derived scaffolds from colorectal cancer reveal clinically critical information.

Salerno, Simona; Ståhlberg, Anders; Holdfeldt, André; Bexe Lindskog, Elinor; Landberg, Göran

Salerno, Simona; Ståhlberg, Anders; Holdfeldt, André; Bexe Lindskog, Elinor; Landberg, Göran.

Afiliação

Salerno S; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Ståhlberg A; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
Holdfeldt A; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.
Bexe Lindskog E; Department of Clinical Genetics and Genomics, Region Västra Götaland, Sahlgrenska University Hospital, Gothenburg, Sweden.
Landberg G; Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Center for Cancer Research, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

J Transl Med ; 20(1): 209, 2022 05 13.

Article em En | MEDLINE | ID: mdl-35562738

Assuntos

Neoplasias Colorretais; Fluoruracila; Neoplasias Colorretais/tratamento farmacológico; Neoplasias Colorretais/genética; Neoplasias Colorretais/patologia; Fluoruracila/farmacologia; Fluoruracila/uso terapêutico; Células HT29; Humanos; Recidiva Local de Neoplasia/patologia; Microambiente Tumoral

Palavras-chave

5-fluorouracil; Colorectal cancer; Decellularized matrix; Drug screening; Patient-derived scaffold

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Fluoruracila Limite: Humans Idioma: En Revista: J Transl Med Ano de publicação: 2022 Tipo de documento: Article

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