Jianpi Huayu decoction inhibits the epithelial-mesenchymal transition of hepatocellular carcinoma cells by suppressing exosomal miR-23a-3p/Smad signaling.

Xie, Chun-Feng; Feng, Kun-Liang; Wang, Ji-Nan; Luo, Rui; Fang, Chong-Kai; Zhang, Ying; Shen, Chuang-Peng; Zhong, Chong

Xie, Chun-Feng; Feng, Kun-Liang; Wang, Ji-Nan; Luo, Rui; Fang, Chong-Kai; Zhang, Ying; Shen, Chuang-Peng; Zhong, Chong.

Afiliação

Xie CF; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; Department of General Surgery, Liuzhou Traditional Chinese Medical Hospital, 545001, Liuzhou, China.
Feng KL; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Wang JN; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Luo R; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Fang CK; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Zhang Y; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; First Clinical Medical College, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China.
Shen CP; Department of Endocrinology, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. Electronic address: shenchuangpeng@gzucm.edu.cn.
Zhong C; Department of Hepatobiliary Surgery, The First Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou, 510405, China; Lingnan Medical Research Center, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. Electronic address: zhongchong1732@gzucm.edu.cn.

J Ethnopharmacol ; 294: 115360, 2022 Aug 10.

Article em En | MEDLINE | ID: mdl-35568116

Assuntos

Carcinoma Hepatocelular; Neoplasias Hepáticas; MicroRNAs; Animais; Carcinoma Hepatocelular/tratamento farmacológico; Carcinoma Hepatocelular/genética; Carcinoma Hepatocelular/metabolismo; Linhagem Celular Tumoral; Movimento Celular; Proliferação de Células; Cromatografia Líquida; Transição Epitelial-Mesenquimal; Regulação Neoplásica da Expressão Gênica; Humanos; Neoplasias Hepáticas/tratamento farmacológico; Neoplasias Hepáticas/genética; Neoplasias Hepáticas/metabolismo; Camundongos; Camundongos Nus; MicroRNAs/genética; MicroRNAs/metabolismo; Transdução de Sinais; Espectrometria de Massas em Tandem; Microambiente Tumoral

Palavras-chave

Epithelial mesenchymal transition; Exosome; Hepatocellular carcinoma; Jianpi huayu decoction; miR-23a-3p

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Carcinoma Hepatocelular / MicroRNAs / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Revista: J Ethnopharmacol Ano de publicação: 2022 Tipo de documento: Article

Texto completo

Imprimir

XML

PubMed Links

Buscar no Google