Oscillation-coordinated, noise-resistant information distribution via the subiculum.
Curr Opin Neurobiol
; 75: 102556, 2022 08.
Article
em En
| MEDLINE
| ID: mdl-35598550
ABSTRACT
The hippocampus processes information associated with spatial navigation. The subiculum receives input from the hippocampus CA1 and projects to various cortical and subcortical regions. Thus, the subiculum is uniquely positioned to distribute hippocampal information to a range of brain areas. Subicular neurons fire at higher rates than CA1 neurons and exhibit similarly or more accurately decodable representations of place, speed, and trajectory. These representations are more noise-resistant and advantageous for long-range information transfer. Subicular neurons selectively or uniformly distribute information to target areas, depending on the information type. Theta oscillations and sharp-wave ripples control information broadcasting in a pathway-specific manner. Thus, the subiculum routes accurately decodable, noise-resistant, navigation-associated information to downstream regions.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hipocampo
/
Neurônios
Idioma:
En
Revista:
Curr Opin Neurobiol
Ano de publicação:
2022
Tipo de documento:
Article