Experimental demonstration of tethered gene drive systems for confined population modification or suppression.

Metzloff, Matthew; Yang, Emily; Dhole, Sumit; Clark, Andrew G; Messer, Philipp W; Champer, Jackson

Metzloff, Matthew; Yang, Emily; Dhole, Sumit; Clark, Andrew G; Messer, Philipp W; Champer, Jackson.

Afiliação

Metzloff M; Department of Computational Biology, Cornell University, Ithaca, NY, 14853, USA.
Yang E; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14853, USA.
Dhole S; Department of Computational Biology, Cornell University, Ithaca, NY, 14853, USA.
Clark AG; Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY, 14853, USA.
Messer PW; Department of Entomology and Plant Pathology, North Carolina State University, Raleigh, NC, 27695, USA.
Champer J; Department of Computational Biology, Cornell University, Ithaca, NY, 14853, USA.

BMC Biol ; 20(1): 119, 2022 05 24.

Article em En | MEDLINE | ID: mdl-35606745

Assuntos

Tecnologia de Impulso Genético; Animais; Sistemas CRISPR-Cas; Repetições Palindrômicas Curtas Agrupadas e Regularmente Espaçadas; Drosophila/genética; Tecnologia de Impulso Genético/métodos

Palavras-chave

CRISPR; Drosophila melanogaster; Gene drive; Population modification; Population suppression; Tethered gene drive; Toxin-antidote confined

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tecnologia de Impulso Genético Limite: Animals Idioma: En Revista: BMC Biol Ano de publicação: 2022 Tipo de documento: Article

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