Fringe GlcNAc-transferases differentially extend O-fucose on endogenous NOTCH1 in mouse activated T cells.

Matsumoto, Kenjiroo; Kumar, Vivek; Varshney, Shweta; Nairn, Alison V; Ito, Atsuko; Pennarubia, Florian; Moremen, Kelley W; Stanley, Pamela; Haltiwanger, Robert S

Matsumoto, Kenjiroo; Kumar, Vivek; Varshney, Shweta; Nairn, Alison V; Ito, Atsuko; Pennarubia, Florian; Moremen, Kelley W; Stanley, Pamela; Haltiwanger, Robert S.

Afiliação

Matsumoto K; Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Kumar V; Department of Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.
Varshney S; Department of Cell Biology, Albert Einstein College of Medicine, New York, New York, USA.
Nairn AV; Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Ito A; Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Pennarubia F; Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Moremen KW; Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA.
Stanley P; Department of Cell Biology, Albert Einstein College of Medicine, New York, New York, USA. Electronic address: pamela.stanley@einsteinmed.edu.
Haltiwanger RS; Complex Carbohydrate Research Center, Department of Biochemistry and Molecular Biology, University of Georgia, Athens, Georgia, USA. Electronic address: rhalti@uga.edu.

J Biol Chem ; 298(7): 102064, 2022 07.

Article em En | MEDLINE | ID: mdl-35623385

Assuntos

Fator de Crescimento Epidérmico; Fucose; Receptor Notch1/metabolismo; Animais; Fator de Crescimento Epidérmico/metabolismo; Fucose/metabolismo; Glucosiltransferases; Glicosiltransferases/genética; Glicosiltransferases/metabolismo; Camundongos; Polissacarídeos/metabolismo; Receptores Notch/metabolismo; Linfócitos T/metabolismo

Palavras-chave

EGF repeats; Notch; O-fucose; T cells; fringe; glycosylation; mass spectrometry

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fator de Crescimento Epidérmico / Receptor Notch1 / Fucose Limite: Animals Idioma: En Revista: J Biol Chem Ano de publicação: 2022 Tipo de documento: Article

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