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Triazoloquinoxalines-based DNA intercalators-Topo II inhibitors: design, synthesis, docking, ADMET and anti-proliferative evaluations.
Elwan, Alaa; Sakr, Helmy; El-Helby, Abdel-Ghany A; El-Morsy, Ahmed; Abdelgawad, Mohamed A; Ghoneim, Mohammed M; El-Sherbiny, Mohamed; El-Adl, Khaled.
Afiliação
  • Elwan A; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
  • Sakr H; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
  • El-Helby AA; Pharmaceutical Medicinal Chemistry & Drug Design Department, Faculty of Pharmacy (Boys), Al-Azhar University, Cairo, Egypt.
  • El-Morsy A; Pharmaceutical Chemistry Department, College of Pharmacy, The Islamic University, Najaf, Iraq.
  • Abdelgawad MA; Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Saudi Arabia.
  • Ghoneim MM; Department of Pharmacy Practice, Faculty of Pharmacy, AlMaarefa University, Ad Diriyah, Saudi Arabia.
  • El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia.
  • El-Adl K; Department of Anatomy, Faculty of Medicine, Mansoura University, Mansoura, Egypt.
J Enzyme Inhib Med Chem ; 37(1): 1556-1567, 2022 Dec.
Article em En | MEDLINE | ID: mdl-35635148
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Topoisomerase II / Substâncias Intercalantes Idioma: En Revista: J Enzyme Inhib Med Chem Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores da Topoisomerase II / Substâncias Intercalantes Idioma: En Revista: J Enzyme Inhib Med Chem Ano de publicação: 2022 Tipo de documento: Article