Blood levels and distribution of talampicillin and bacampicillin in NZW rabbits.
Tokai J Exp Clin Med
; 11(2): 91-9, 1986 May.
Article
em En
| MEDLINE
| ID: mdl-3564081
ABSTRACT
Parameters for blood concentrations of the peroral antibiotics talampicil in and bacampicillin, in NZW rabbits were determined using a two compartment model. On the basis of these pharmacokinetic parameters, a three compartment model was prepared for the concentrations of these drugs in the tongue, gingiva, submandibular gland, parotid gland, cervical lymph-node and mandibular bone. Simulation curves based on the parameters of tissue concentrations revealed visual conformity to the measured values.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Talampicilina
/
Ampicilina
Limite:
Animals
Idioma:
En
Revista:
Tokai J Exp Clin Med
Ano de publicação:
1986
Tipo de documento:
Article