The ROS-generating enzyme NADPH oxidase 1 modulates the colonic microbiota but offers minor protection against dextran sulfate sodium-induced low-grade colon inflammation in mice.

Herfindal, Anne Mari; Rocha, Sérgio Domingos Cardoso; Papoutsis, Dimitrios; Bøhn, Siv Kjølsrud; Carlsen, Harald

Herfindal, Anne Mari; Rocha, Sérgio Domingos Cardoso; Papoutsis, Dimitrios; Bøhn, Siv Kjølsrud; Carlsen, Harald.

Afiliação

Herfindal AM; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, P. O. Box 5003, N-1432, Ås, Norway. Electronic address: anne.mari.herfindal@nmbu.no.
Rocha SDC; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, P. O. Box 5003, N-1432, Ås, Norway; Faculty of Biosciences, Norwegian University of Life Sciences, P. O. Box 5003, N-1432, Ås, Norway. Electronic address: sergio.rocha@nmbu.no.
Papoutsis D; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, P. O. Box 5003, N-1432, Ås, Norway. Electronic address: dimitrios.papoutsis@nmbu.no.
Bøhn SK; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, P. O. Box 5003, N-1432, Ås, Norway. Electronic address: siv.kjolsrud.bohn@nmbu.no.
Carlsen H; Faculty of Chemistry, Biotechnology and Food Science, Norwegian University of Life Sciences, P. O. Box 5003, N-1432, Ås, Norway. Electronic address: harald.carlsen@nmbu.no.

Free Radic Biol Med ; 188: 298-311, 2022 08 01.

Article em En | MEDLINE | ID: mdl-35752373

Assuntos

Colite; Microbiota; NADPH Oxidase 1; Animais; Colite/induzido quimicamente; Colite/genética; Colite/metabolismo; Colo/microbiologia; Sulfato de Dextrana/toxicidade; Inflamação; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Knockout; NADPH Oxidase 1/genética; NADPH Oxidase 1/metabolismo; NADPH Oxidases/genética; RNA Ribossômico 16S/genética; Espécies Reativas de Oxigênio/farmacologia

Palavras-chave

Dextran sulfate sodium; Gut inflammation; Intestinal microbiota; NADPH oxidase 1 (NOX1); Reactive oxygen species (ROS)

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Colite / Microbiota / NADPH Oxidase 1 Limite: Animals Idioma: En Revista: Free Radic Biol Med Ano de publicação: 2022 Tipo de documento: Article

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