MEDETOMIDINE-KETAMINE-BUPRENORPHINE ANESTHESIA OF THE SOLITARY SUBTERRANEAN CAPE DUNE MOLE-RAT (BATHYERGUS SUILLUS) AND THE CAPE MOLE-RAT (GEORYCHUS CAPENSIS).
J Zoo Wildl Med
; 53(2): 357-362, 2022 Jun.
Article
em En
| MEDLINE
| ID: mdl-35758577
ABSTRACT
A prospective, descriptive study was conducted to evaluate the safety and efficacy of a field-ready anesthetic drug combination of medetomidine-ketamine-buprenorphine for data logger implantation surgery or recheck in free-ranging Cape dune (Bathyergus suillus n = 41) and Cape (Georychus capensis n = 37) mole-rats. All anesthesia data were reported as mean (±standard deviation). Medetomidine-ketamine-buprenorphine doses were 0.1 (±0.03), 10.6 (±2.8), and 0.06 (±0.03) mg/kg, respectively, for Cape dune mole-rats; and 0.2 (±0.03), 19.4 (±4.0), and 0.14 (±0.03) mg/kg, respectively, for Cape mole-rats. Induction was calm and took 2.00 (range 1.00-6.00) min for the Cape dune and 1.75 (range 1.25 to 8.16) min for Cape mole-rats. A surgical plane of anesthesia was achieved in most Cape dune mole-rats (92%) and Cape mole-rats (90%). The remainder required supplementation with a single intramuscular injection of ketamine (3-9 mg/kg) during surgery. Heart and respiratory rates were 149 (±37) beats and 24 (±8) breaths per minute, respectively, for Cape dune mole-rats and 179 (±40) beats and 25 (±10) and breaths per minute, respectively for Cape mole-rats. Surgical time for mole-rats ranged from 25 to 38 min. Recovery was calm and took 8.50 (range 2.00-19.00) min for Cape dune mole-rats and 9.75 (range 2.00-34.00) min for Cape mole-rats to recover. For recovery, atipamezole was administered intramuscularly at 0.5 (±0.15) mg/kg for Cape dune mole-rats and 1 (±0.15) mg/kg for Cape mole-rats. All mole-rats were returned to their original burrows within 48 h of recovery. The medetomidine-ketamine-buprenorphine combination induced a predictable, safe anesthesia in Cape dune and Cape mole-rats suitable for short intraabdominal surgery. This combination is suited to in situ studies where the use of a formal surgery or laboratory is not feasible.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Buprenorfina
/
Anestesia
/
Ketamina
Tipo de estudo:
Observational_studies
/
Risk_factors_studies
Limite:
Animals
Idioma:
En
Revista:
J Zoo Wildl Med
Ano de publicação:
2022
Tipo de documento:
Article