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Cancer-associated fibroblasts require proline synthesis by PYCR1 for the deposition of pro-tumorigenic extracellular matrix.
Kay, Emily J; Paterson, Karla; Riera-Domingo, Carla; Sumpton, David; Däbritz, J Henry M; Tardito, Saverio; Boldrini, Claudia; Hernandez-Fernaud, Juan R; Athineos, Dimitris; Dhayade, Sandeep; Stepanova, Ekaterina; Gjerga, Enio; Neilson, Lisa J; Lilla, Sergio; Hedley, Ann; Koulouras, Grigorios; McGregor, Grace; Jamieson, Craig; Johnson, Radia Marie; Park, Morag; Kirschner, Kristina; Miller, Crispin; Kamphorst, Jurre J; Loayza-Puch, Fabricio; Saez-Rodriguez, Julio; Mazzone, Massimiliano; Blyth, Karen; Zagnoni, Michele; Zanivan, Sara.
Afiliação
  • Kay EJ; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Paterson K; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Riera-Domingo C; Centre for Microsystems and Photonics, EEE Department, University of Strathclyde, Glasgow, UK.
  • Sumpton D; Laboratory of Tumor Inflammation and Angiogenesis, Center for Cancer Biology (CCB), VIB, Leuven, Belgium.
  • Däbritz JHM; Laboratory of Tumor Inflammation and Angiogenesis, Department of Oncology, KU Leuven, Leuven, Belgium.
  • Tardito S; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Boldrini C; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Hernandez-Fernaud JR; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Athineos D; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Dhayade S; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Stepanova E; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Gjerga E; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Neilson LJ; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Lilla S; Translational Control and Metabolism, German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Hedley A; Heidelberg University, Faculty of Medicine, Institute for Computational Biomedicine, Bioquant, Heidelberg, Germany.
  • Koulouras G; RWTH Aachen University, Faculty of Medicine, Joint Research Centre for Computational Biomedicine (JRC-COMBINE), Aachen, Germany.
  • McGregor G; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Jamieson C; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Johnson RM; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Park M; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Kirschner K; Cancer Research UK Beatson Institute, Glasgow, UK.
  • Miller C; Institute of Cancer Sciences, University of Glasgow, Glasgow, UK.
  • Kamphorst JJ; Department of Pure and Applied Chemistry, Thomas Graham Building, University of Strathclyde, Glasgow, UK.
  • Loayza-Puch F; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.
  • Saez-Rodriguez J; Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Quebec, Canada.
  • Mazzone M; Department of Biochemistry, McGill University, Montreal, Quebec, Canada.
  • Blyth K; Department of Medicine, McGill University, Montreal, Quebec, Canada.
  • Zagnoni M; Department of Oncology, McGill University, Montreal, Quebec, Canada.
  • Zanivan S; Cancer Research UK Beatson Institute, Glasgow, UK.
Nat Metab ; 4(6): 693-710, 2022 06.
Article em En | MEDLINE | ID: mdl-35760868
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolina Carboxilato Redutases / Neoplasias da Mama / Fibroblastos Associados a Câncer Tipo de estudo: Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Nat Metab Ano de publicação: 2022 Tipo de documento: Article
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirrolina Carboxilato Redutases / Neoplasias da Mama / Fibroblastos Associados a Câncer Tipo de estudo: Risk_factors_studies Limite: Female / Humans Idioma: En Revista: Nat Metab Ano de publicação: 2022 Tipo de documento: Article