Contribution of Humanized Liver Chimeric Mice to the Study of Human Hepatic Drug Transporters: State of the Art and Perspectives.

Zerdoug, Anna; Le Vée, Marc; Uehara, Shotaro; Lopez, Béatrice; Chesné, Christophe; Suemizu, Hiroshi; Fardel, Olivier

Zerdoug, Anna; Le Vée, Marc; Uehara, Shotaro; Lopez, Béatrice; Chesné, Christophe; Suemizu, Hiroshi; Fardel, Olivier.

Afiliação

Zerdoug A; University of Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail)-UMR_S 1085, 35000, Rennes, France.
Le Vée M; Biopredic International, 35760, Saint Grégoire, France.
Uehara S; University of Rennes, Inserm, EHESP, Irset (Institut de Recherche en Santé, Environnement et Travail)-UMR_S 1085, 35000, Rennes, France.
Lopez B; Central Institute for Experimental Animals, Kawasaki, 210-0821, Japan.
Chesné C; Biopredic International, 35760, Saint Grégoire, France.
Suemizu H; Biopredic International, 35760, Saint Grégoire, France.
Fardel O; Central Institute for Experimental Animals, Kawasaki, 210-0821, Japan.

Eur J Drug Metab Pharmacokinet ; 47(5): 621-637, 2022 Sep.

Article em En | MEDLINE | ID: mdl-35793042

Assuntos

Hepatócitos; Fígado; Animais; Quimera/metabolismo; Hepatócitos/metabolismo; Humanos; Fígado/metabolismo; Proteínas de Membrana Transportadoras/metabolismo; Taxa de Depuração Metabólica; Camundongos

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Hepatócitos / Fígado Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Eur J Drug Metab Pharmacokinet Ano de publicação: 2022 Tipo de documento: Article

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